Early Stage Cervical Cancer
Conditions
Interventions
TARH:TARH
Laparoscopic surgery based on the open stateGasless TLRH:Laparoscopic surgery based on the open state
Sponsors
Shenyang Women's and Children's Hospital
Eligibility
Sex/Gender
Female
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Patients with cervical adenocarcinoma, squamous cell carcinoma, or adenosquamous carcinoma who are at least 18 years old; 2. Patients with ECOG presentation status of 0-1 and FIGO (2018) clinical staging of IA1 disease with lymphatic vessel invasion, IA2 disease or IB1 disease (<2 cm, limited to cervix) were randomly divided into open or minimally invasive radical hysterectomy in a 1:1 ratio; 3. Patients can undergo type II or III radical hysterectomy (Piver classification) and pelvic lymph node resection. According to the Sedlis standard, postoperative adjuvant radiotherapy is recommended and widely accepted.
Exclusion criteria
Exclusion criteria: 1. Neuroendocrine, transparent or serous cell types; 2. Clinical advanced diseases with tumor size greater than 4cm (IB2-IV stage); 3. Uterine size greater than 12 centimeters, history of abdominal or pelvic radiation therapy, or evidence of metastatic disease on positron emission tomography (computed tomography, magnetic resonance imaging, or computed tomography); 4. If researchers believe that patients are unable to undergo surgery or cannot withstand the lithotomy position, they will also be excluded. Or lack compliance or reside too far away from the treatment center, making it impossible to conduct sufficient follow-up.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Disease free survival;Length of stay; | — |
Secondary
| Measure | Time frame |
|---|---|
| Recurrence rates;Postoperative pain ;The Quality of Life;Operation time;Estimated blood loss;operative complications;The levels of CD4 + T lymphocytes, NK cells and CD4 + CD25 high CD127 low Treg;Hemodynamic parameters;MAP;SV;Costs; | — |
Countries
China
Contacts
Public ContactYansong Liu
Shenyang Women's and Children's Hospital
Outcome results
None listed