Radical surgery for colon and rectal cancer
Conditions
Interventions
one:Test group (lipid bupivacaine group): 1.3% of lipid bupivacaine 10 mL plus saline 20 mL totaling 30 mL.
two :Control group (common bupivacaine group): inject 10 mL of 0.75% bupivacaine plus 20 mL of normal saline per side for a total of 30 mL.
Sponsors
The General Hospital of Ningxia Medical University
Eligibility
Sex/Gender
All
Age
60 Years to 80 Years
Inclusion criteria
Inclusion criteria: Patients undergoing elective laparoscopic radical resection of colorectal cancer, aged 60 to 80 years, ASA grades II to III, BMI 18 to 28 kg/m2, and signed informed consent.
Exclusion criteria
Exclusion criteria: 1. allergic to opioid, amide local anesthetics and non-steroidal anti-inflammatory drugs; 2. Long-term use of analgesic and sedative drugs; 3. Definitive diagnosis of coronary heart disease; 4. Severe heart, lung, liver, brain and kidney diseases; 5. History of alcohol and drug abuse;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Area under the curve of resting pain and motor pain scores from 12 h to 72 h after surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| Consumption of analgesic drugs;Time for first relief of pain relief;Number of times to remedy pain relief;Adverse reactions;Length of hospitalization;Satisfaction;sleep quality; | — |
Countries
China
Contacts
Public ContactLiqin Deng
The General Hospital of Ningxia Medical University
Outcome results
None listed