Multiple intestinal polyps
Conditions
Interventions
Group R0 (0.5ug/kg.h):Remazolam (0.5 mg/kg.h) was injected continuously during the operation, and remifentanil was injected with 0.5ug/kg.h combined pump
Group R1(1ug/kg.h):Remazolam (0.5 mg/kg.h) was injected continuously during the operation, and remifentanil was injected with 1ug/kg.h combined pump
Group R2(1.5ug/kg.h):Remazolam (0.5 mg/kg.h) was injected continuously during the operation, and remifentanil was injected with 1.5ug/kg.h combined pump
Group R3(2ug/kg.h):Remazolam (0.5 mg/kg.h) was injected continuously during the operation, and remifentanil was injected with2ug/kg.h combined pump
Sponsors
Liaocheng People’s Hospital
Eligibility
Sex/Gender
All
Age
40 Years to 80 Years
Inclusion criteria
Inclusion criteria: ?Age: 40 ~ 80 years old. ?ASA grades ? to ?. ? No sedation-related drugs were used within 1 month before enrollment. ? Understand the study content, the patient or family members have signed the informed consent.
Exclusion criteria
Exclusion criteria: ? Complicated with malignant tumor, coagulation function or liver and kidney dysfunction. ? There is severe respiratory insufficiency. ? Complicated with serious heart and cerebrovascular diseases. Allergy to the narcotic drugs involved in the study. ? Excessive obesity (BMI above 35kg/m2). ? Poor cooperation, combined with serious mental illness or cognitive dysfunction.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Blood oxygen saturation;Mean arterial pressure;Heart rate;bradycardia; | — |
Secondary
| Measure | Time frame |
|---|---|
| Operation time;recovery time;PACU residence time;orientation recovery time;Record the dose and number of pressors required during the operation;The incidence of somatokinetic reaction;respiratory depression;hypotension;hiccup;postoperative dizziness, nausea and vomiting;lethargy;abdominal pain and distension; | — |
Countries
China
Contacts
Public ContactXiangrong Du
Department of Anesthesiology, Liaocheng People’s Hospital, Liaocheng City, PR China,
Outcome results
None listed