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The effects of esketamine-combined ropivacaine on repound pain of upper limb fracture after brachial plexus blockade

The effects of esketamine-combined ropivacaine on repound pain of upper limb fracture after brachial plexus blockade

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300075083
Enrollment
Unknown
Registered
2023-08-24
Start date
2023-09-01
Completion date
Unknown
Last updated
2023-08-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Repound pain of upper limb fracture after brachial plexus blockade

Interventions

Adjuvant group for brachial plexus block (Group N):Brachial plexus block with ropivacaine combined with esketamine
Intravenous esketaminegroup (Group V):Brachial plexus block with ropivacaine +Intravenous esketamine
Control group (Group C):Brachial plexus block with ropivacaine

Sponsors

The People's Hospital of Deyang City
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. ASA I to III 2. Age 18~60 years old 3. BMI 18-30kg /m2 4.Unilateral upper limb fracture surgery with internal fixation of steel plate 5.An electric pneumatic tourniquet was placed on 1/3 of the upper arm. The total time of tourniquet was =3h, and the total operation time was =4h

Exclusion criteria

Exclusion criteria: 1.Combined with fractures or severe trauma in other parts 2.History of contraindications or allergies 3.With severe cardiovascular, kidney and liver diseases 4. Mental illness, mental illness, low cognitive ability, etc., resulting in cooperation and communication difficulties 5.Drug and alcohol abuse 6.Use of analgesic, sedative or hormonal drugs for > 2 weeks before surgery 7.Brachial plexus anesthesia could not be performed due to coagulation dysfunction and puncture site infection; 8.Pregnant, lactating and pregnant women 9. Electromyography indicated nerve injury. 10. Iliac bone graft from the body is required.

Design outcomes

Primary

MeasureTime frame
Incidence of repound pain;

Secondary

MeasureTime frame
Onset of repound pain;Scores of repound pain;

Countries

China

Contacts

Public ContactYukai Zhou

The People's Hospital of Deyang City

yukaizhou@foxmail.com+86 187 8105 4070

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 5, 2026