Skip to content

Comparative Study of Remazolam and Propofol Assisted Sedation in Intraspinal Anesthesia for Caesarean section

Comparative Study of Remazolam and Propofol Assisted Sedation in Intraspinal Anesthesia for Caesarean section

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300075070
Enrollment
Unknown
Registered
2023-08-24
Start date
2023-09-01
Completion date
Unknown
Last updated
2023-08-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Obstetrics and Gynecology Diseases

Interventions

Remazolam R1 group:Anesthesia induction: intravenous injection of 0.2mg/kg remidazolam. Anesthesia maintenance: intravenous infusion of Remazolam 0.1mg/kg/h
Remazolam R2 group:Anesthesia induction: intravenous injection of 0.2mg/kg remidazolam. Anesthesia maintenance: intravenous infusion of Remazola 0.2mg/kg/h
Remazolam R2 group:Anesthesia induction: intravenous injection of 0.2mg/kg remidazolam. Anesthesia maintenance: intravenous infusion of Remazola 0.3mg/kg/h
Propofol group:Anesthesia induction: intravenous injection of propofol 2mg/kg, anesthesia maintenance: intravenous pump injection of propofol 5mg/kg/h

Sponsors

Guangzhou Women and Children's Medical Center Liuzhou Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Maternity with age = 18 years, BMI 18-31 kg/m2, ASA grade I or II, and elective Caesarean section

Exclusion criteria

Exclusion criteria: A. Maternity with serious Respiratory disease and circulatory system disease; B. Pregnant women with severe liver and kidney dysfunction; C. Pregnant women with respiratory dysfunction such as sleep apnea; D. Maternity taking sedative and analgesic drugs for a long time; E. Maternal women who are allergic to benzodiazepines Drug allergy, schizophrenic, and severely depressed

Design outcomes

Primary

MeasureTime frame
heart rate; blood pressure; respiratory rate;Pulse Oxygen Saturation;Improved vigilance/sedation observation score;

Countries

China

Contacts

Public ContactHu Jing

Guangzhou Women and Children's Medical Center Liuzhou Hospital

15077202268@139.com+86 150 7720 2268

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026