Hypertrophy of tonsil in children
Conditions
Interventions
Group K3:Esketamine 0.5mg/kg
Group K1:Esketamine 0.1mg/kg
Group K2:Esketamine 0.3mg/kg
Group K0:Esketamine 0mg/kg
Sponsors
Affiliated Hospital of North Sichuan Medical College
Eligibility
Sex/Gender
All
Age
3 Years to 10 Years
Inclusion criteria
Inclusion criteria: A total of 164 children with tonsil or adenoid hypertrophy aged 3 ~ 10 years were included. BMI 18-28 kg/m2; ASA grade ?-?; Preoperative physical examination showed no abnormality in cardiopulmonary function and normal liver and kidney function.
Exclusion criteria
Exclusion criteria: Patients who had emergency surgery, a history of allergy to opioid or non-opioid analgesics, a history of respiratory infection or asthma, developmental delays or psychiatric disorders associated with symptoms such as irritability, anxiety, attention deficit, sleep disturbance, or cognitive impairment, children who had difficulty with the preoperative assessment, or were unable to complete the trial for other reasons.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Agitation Score (PAED Score);Agitation Score (Watcha Score);Heart rate;Systolic blood pressure; | — |
Secondary
| Measure | Time frame |
|---|---|
| Calm score (Ramsay score);The duration and frequency of postoperative agitation; | — |
Countries
China
Contacts
Public ContactPingPing Jiang
Affiliated Hospital of North Sichuan Medical College
Outcome results
None listed