Coronary drug-eluting in-stent restenosis
Conditions
Interventions
Experimental group:The "three-step" process of optical coherence tomography guiding interventional therapy for restenosis in drug-eluting stents
Sponsors
Department of Cardiology,First Medical Center of Chinese PLA General Hospital,Beijing 100853,China
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. 18 to 80 years old; 2. The diameter of the vascular reference lumen in patients with restenosis in drug-eluting stents was 2.5-4.0mm, and the length of the lesion was no more than 30mm; 3. Diameter stenosis =70% or =50% with evidence of myocardial ischemia.
Exclusion criteria
Exclusion criteria: 1. Acute myocardial infarction within 1 week; 2. Left main or right coronary artery opening lesions; 3. Bifurcation lesions; 4. Intraarterial lesions of bypass transplantation; 5. Severe chronic heart failure or NYHA Level IV; 6. Severe heart valvular disease; 7. Stroke within 6 months before intervention; 8. Severe kidney failure; 9. Recurrent in-stent restenosis.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Preoperative minimum lumen diameter;Minimum lumen diameter post-procedure;Angiographic follow-up minimum lumen diameter;Late lumen loss; | — |
Secondary
| Measure | Time frame |
|---|---|
| Lesion length;Reference lumen diameter;Distal reference lumen area;Proximal reference lumen area;Minimum lumen area;Neointimal thickness;Neointimal area;Stent length;Maximum Angle of lipid arc;Fibercap thickness;Plaque properties;Plaque distribution characteristics;The backscatter case;Thin fibrous cap atherosclerotic plaque;Macrophage infiltration;Characteristics and distribution of thrombus; | — |
Countries
China
Contacts
Public ContactLei Gao
Department of Cardiology,First Medical Center of Chinese PLA General Hospital,Beijing 100853,China
Outcome results
None listed