sepsis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Sepsis group: Aged >18 years; Meet the diagnostic criteria of sepsis 3.0; Patients and their families gave informed consent to the study protocol; 2. Non-infected control group: Age- and sex-matched patients undergoing surgery or non-infectious trauma; 3. Healthy control group: Age- and sex-matched healthy blood donors.
Exclusion criteria
Exclusion criteria: 1. HIV-positive patients; 2. Patients with autoimmune disease; 3. Patients taking immunosuppressive drugs; 4. Pregnant and unable to provide informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| lactylation level of immune cells; | — |
Secondary
| Measure | Time frame |
|---|---|
| sequential organ failure assessment score;acute physiology and chronic health evaluation II score;serum biochemical index;28 days mortality;Length of stay in ICU;Length of stay; | — |
Countries
China
Contacts
The First Affiliated Hospital of Zhejiang University School of Medicine