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Early warning and progress monitoring of traumatic sepsis

Early warning and progress monitoring of traumatic sepsis

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300075000
Enrollment
Unknown
Registered
2023-08-22
Start date
2021-12-07
Completion date
Unknown
Last updated
2025-03-31

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

sepsis

Interventions

Healthy control group:N/A
Non-infected control group:N/A

Sponsors

The First Affiliated Hospital of Zhejiang University School of Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Sepsis group: Aged >18 years; Meet the diagnostic criteria of sepsis 3.0; Patients and their families gave informed consent to the study protocol; 2. Non-infected control group: Age- and sex-matched patients undergoing surgery or non-infectious trauma; 3. Healthy control group: Age- and sex-matched healthy blood donors.

Exclusion criteria

Exclusion criteria: 1. HIV-positive patients; 2. Patients with autoimmune disease; 3. Patients taking immunosuppressive drugs; 4. Pregnant and unable to provide informed consent.

Design outcomes

Primary

MeasureTime frame
lactylation level of immune cells;

Secondary

MeasureTime frame
sequential organ failure assessment score;acute physiology and chronic health evaluation II score;serum biochemical index;28 days mortality;Length of stay in ICU;Length of stay;

Countries

China

Contacts

Public ContactFang Xiangming

The First Affiliated Hospital of Zhejiang University School of Medicine

xmfang@zju.edu.cn+86 138 5716 1019

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026