Stroke
Conditions
Interventions
experimental group :active CRB-iTBS+RAGT
control group:sham CRB-iTBS+RAGT
Sponsors
China Rehabilitation Research Center
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1: First onset or past onset without significant sequelae (pre-stroke Modified Rankin Scale score (mRS) =1) 2: Meet the diagnostic criteria for ischemic stroke or hemorrhagic stroke. The duration of the disease is greater than 2 weeks and less than 6 months 3: Aged between 18 and 75 years (including 18 and 75 years) 4: FAC < 4 due to unilateral hemispheric stroke 5: Who understands the trial and signs the informed consent
Exclusion criteria
Exclusion criteria: 1: Neurological impairment, restriction of lower limb activity, mutilation, joint swelling, contracture, severe pain or other lower limb disorders caused by stroke, brain tumor, brain trauma, fracture, and other diseases caused by bilateral hemispheres or supratentorial lesions 2: The MAS scores of hip, knee, ankle, and toe muscle tension of the affected lower extremity are =3 3: Patients with pacemakers, cochlear implants, or other metallic foreign bodies and any electronic devices implanted in the body are contraindicated for TMS treatment 4: History of epilepsy 5: Patients with severe heart, lung, liver, kidney, and other systemic diseases that conventional drugs could not control were found through laboratory tests and examinations 6: Patients with severe aphasia (NIHSS speech item =2 points), dyslexia (NIHSS phonology item =2 points), cognitive impairment (MMSE score =20 points), deafness, etc., can not cooperate with treatment and evaluation 7: Patients with severe depression, anxiety, or a diagnosis of another mental illness. 8: A history of alcohol or drug abuse. 9: Participate in other clinical research trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fugl-Meyer Motor Assessment Scale-Lower Extremity ; | — |
Secondary
| Measure | Time frame |
|---|---|
| Berg Balance Scale ;Functional Ambulation Category ;Stroke Impact Scale ;Modified Barthel Index; | — |
Countries
China
Contacts
Public ContactHaitao Lu
China Rehabilitation Research Center
Outcome results
None listed