Diabetic foot
Conditions
Interventions
Diagnosed diabetes, taking medicine regularly and having no symptoms related to diabetic foot.:NA
Wagner scale 0~1 diabetic foot patients.:NA
Patients with diabetic foot with Wagner scale 2~5.:NA
Sponsors
Nanjing nanyao medicine technology co., ltd
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1) The sample comes from the remaining samples of clinical testing, and the remaining sample size meets the following requirements: =1 mL of human serum samples; 2) Meet the storage requirements, that is, the samples must be stored at room temperature after collection and centrifuged within 12 hours after collection. And then stored in the dark at-60 DEG C until analysis; 3) The patient's age is =18 years old, regardless of sex; 4) The body mass index (BMI) at screening is between 18.5 and 30 kg/m2 (inclusive); 5) Patients with clinically diagnosed diabetes meet one of the following three conditions: A) Diagnosing diabetes, taking medicine regularly and having no symptoms related to diabetic foot; B) diabetic foot patients with b) Wagner classification method (0~1); C) patients with diabetic foot with c) Wagner classification method.
Exclusion criteria
Exclusion criteria: 1) The sample shows coagulation or hemolysis; 2) Incorrect collection or storage of samples; 3) screening for hyperthyroidism or hypothyroidism that has not been well treated; 4) Patients with systolic blood pressure =180 mmHg and/or diastolic blood pressure =110 mmHg during screening; 5) Suffering from hypokalemia, hypocalcemia or hypocalcemia at the time of screening; 6) When screening, any laboratory inspection index meets the following standards: A) alanine aminotransferase > 2.0× ULN and/or aspartate aminotransferase > 2.0× ULN and/or total bilirubin > >1.5×ULN;; B) serum creatinine > 1.5 × uln (except for diabetic foot patients with Wagner classification 2~5); C) glomerular filtration rate (EGFR) 5.7mmol/L and cholesterol > 1.5×ULN;; F) Patients with abnormal hemoglobin and clinical significance as judged by the researcher (except diabetic foot patients with Wagner classification 2~5); G) TSH > 10 MIU/L, and it has clinical significance as judged by researchers; 7) HBsAg positive, HCV antibody positive, HIV antibody positive, and/or Treponema pallidum antibody positive; 8) Drug, alcohol dependence or history of abuse (drinking 21 units of alcohol every week: 1 unit = 360 mL of beer, 45 mL of spirits or 150 mL); of wine); 9) Patients with major physical diseases such as neurological diseases, brain trauma, cardiovascular and cerebrovascular diseases, and severe liver and kidney dysfunction; 10) pregnant or lactating women; 11) Patients with surgery or other major medical history within 6 months; 12) being treated with hormone drugs; 13) Patients who the researcher thinks are not suitable to participate in this trial due to other factors.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Serum metabolites; | — |
Countries
China
Contacts
Public ContactYanmeiLiu
Director of endocrinology department
Outcome results
None listed