vitiligo
Conditions
Interventions
Group of topical:Remezepam ointment for external use
Group of topical with phototherapy:Remezepam ointment for external use with phototherapy
Sponsors
Third Hospital of Hangzhou
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1: = 18 years old and = 65 years old, regardless of gender. 2: According to the Vitiligo diagnosis and treatment consensus, the researcher believes that the subject is suitable for local treatment of Vitiligo. 3: There are more than 2 target lesions in the face, neck or trunk area, and each lesion should have a diameter of at least 0.1 palm area observed and photographed. 4: score of VIDA<4, local lesions in stable and progressive stages are all OK. 5: Women with fertility potential must be negative in screening period and Pregnancy test before randomization. 6: Fully understand the experimental content, voluntarily participate in the experiment, and sign an informed consent form.
Exclusion criteria
Exclusion criteria: 1: Segmental Vitiligo, acral Vitiligo or mucosal Vitiligo. 2: Patients in rapid progress stage are receiving systematic treatment (such as oral glucocorticoid or JAK inhibitor or other Immunosuppressive drug) within 4 weeks before the test, or target skin lesions are being treated with glucocorticoid, Calcineurin inhibitor, PDE-4 inhibitor, etc. 3: Active autoimmune diseases (such as atopic dermatitis, alopecia areata, Thyroid disease), infectious diseases such as hepatitis B and hepatitis C, Cerebrovascular disease, severe ECG abnormalities, severe or progressive or uncontrolled kidney, liver, blood, digestion, metabolism, endocrine, lung, cardiovascular or Nervous system disease 4: The laboratory test values during screening have clinical significance, and the researcher determines that it is not suitable to participate in the study. 5: The following vulnerable groups will not be included in the study: individuals with mental illness, critically ill patients, pregnant women, minors, cognitive impairment individuals, students of PI or researchers, subordinates of PI or co researchers, employees of research institutions or applicants.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| vitiligo area scoring index, VASI; | — |
Countries
China
Contacts
Public ContactAi-e Xu
Third Hospital of Hangzhou
Outcome results
None listed