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Study on the influence and mechanism of vagus nerve function regulation on myocardial injury after non-cardiac surgery

Study on the influence and mechanism of vagus nerve function regulation on myocardial injury after non-cardiac surgery

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300074973
Enrollment
Unknown
Registered
2023-08-22
Start date
2023-09-01
Completion date
Unknown
Last updated
2023-08-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients with high-risk surgery for cardiovascular complications

Interventions

Non-electric stimulation group:None
Preoperative vagus nerve electrical stimulation group:Auricle percutaneous nerve electrical stimulation
Intraoperative vagus nerve electrical stimulation group:Auricle percutaneous nerve electrical stimulation
Postoperative vagus nerve electrical stimulation group:Auricle percutaneous nerve electrical stimulation

Sponsors

Jin Cheng People Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
45 Years to 99 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: This study included 612 subjects, age = 45 years old, = 1 cardiovascular complication risk factor: coronary heart disease, heart failure, cerebrovascular disease, diabetes, chronic renal failure, peripheral arterial disease, hypertension or age = 65 years old, can be combined with or not combined with high cardiovascular complications Critical factors. It is planned to undergo abdominal surgery under general anesthesia, and the estimated operation time is more than 3 hours.

Exclusion criteria

Exclusion criteria: Exclusion criteria: If you do not meet the inclusion requirements, you will be excluded.

Design outcomes

Primary

MeasureTime frame
hs-cTnI ;

Secondary

MeasureTime frame
Perioperative hypotension incidence, duration, vascular active drug dosage, cardiovascular complications and postoperative 30 days mortality.;

Countries

China

Contacts

Public ContactWang Jinping

Jin Cheng People Hospital

jmjtwjp@163.com+86 135 9334 0817

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026