Knee osteoarthritis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: ?No abnormalities in rheumatoid, rheumatic, self-funding and infection index tests; ?No medical comorbidities, x-ray arthritis grading (K-L typing) grade 2 for mild knee osteoarthritis and K-L typing grade 4 for severe arthritis. No previous history of knee trauma or surgery, and no extra-articular deformities; ?Normal fecal parasite testing and no previous history of abnormal bowel movements or episodes of gastrointestinal disease; ?No previous history of prolonged antibiotic administration; ? Those who voluntarily joined this study and signed the informed consent form.
Exclusion criteria
Exclusion criteria: ?Patients who need to take immunosuppressants for a long time, antibiotics for >1 year; ?Chronic enteritis, those with recurrent diarrhea in the past 1 month, patients with intestinal cancer, those who have undergone intestinal surgery.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Intestinal flora; | — |
Secondary
| Measure | Time frame |
|---|---|
| Traditional Chinese Medicine Body Types;metabolomics; | — |
Countries
China
Contacts
Guangdong Provincial Hospital of Traditional Chinese Medicine