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Correlation of intestinal flora and metabolomic differences between Guangdong and Mongolia populations with osteoarthritis of the knee based on constitution identification

Correlation of intestinal flora and metabolomic differences between Guangdong and Mongolia populations with osteoarthritis of the knee based on constitution identification

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300074965
Enrollment
Unknown
Registered
2023-08-22
Start date
2022-07-10
Completion date
Unknown
Last updated
2023-08-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Knee osteoarthritis

Interventions

Guangdong Regional Group:N/A
Inner Mongolia Regional Group:N/A

Sponsors

Guangdong Provincial Hospital of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
50 Years to 80 Years

Inclusion criteria

Inclusion criteria: ?No abnormalities in rheumatoid, rheumatic, self-funding and infection index tests; ?No medical comorbidities, x-ray arthritis grading (K-L typing) grade 2 for mild knee osteoarthritis and K-L typing grade 4 for severe arthritis. No previous history of knee trauma or surgery, and no extra-articular deformities; ?Normal fecal parasite testing and no previous history of abnormal bowel movements or episodes of gastrointestinal disease; ?No previous history of prolonged antibiotic administration; ? Those who voluntarily joined this study and signed the informed consent form.

Exclusion criteria

Exclusion criteria: ?Patients who need to take immunosuppressants for a long time, antibiotics for >1 year; ?Chronic enteritis, those with recurrent diarrhea in the past 1 month, patients with intestinal cancer, those who have undergone intestinal surgery.

Design outcomes

Primary

MeasureTime frame
Intestinal flora;

Secondary

MeasureTime frame
Traditional Chinese Medicine Body Types;metabolomics;

Countries

China

Contacts

Public ContactDa Guo

Guangdong Provincial Hospital of Traditional Chinese Medicine

wsszygd123@163.com+86 139 2646 4394

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026