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Study of serum peptidomic profiles aid early-stage lung cancer diagnosis

Study of serum peptidomic profiles aid early-stage lung cancer diagnosis

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300074955
Enrollment
Unknown
Registered
2023-08-21
Start date
2023-09-01
Completion date
Unknown
Last updated
2023-08-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pulmonary nodule and lung cancer

Interventions

Gold Standard:Pathological diagnostic report and CT examination reports of more than 2 years.
Index test:Serum peptide fingerprint map

Sponsors

Zhongshan Hospital Affiliated to Fudan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
35 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Age range of 35-80 years with a mean of 60 years, following a normal distribution, and a male-to-female ratio of 2:1. 2. Complete clinical information, pathology report, and imaging data including CT scans. 3. Voluntarily participating in this project, signing an informed consent form, and willing to provide questionnaire survey information on smoking history, occupational exposure history, medical history, and familial history of lung cancer within three generations.

Exclusion criteria

Exclusion criteria: 1. Suffering from tuberculosis, bacterial pneumonia, pulmonary infections caused by other pathogens (such as Mycoplasma pneumoniae, Chlamydia pneumoniae, viruses, etc.), infectious atypical pneumonia, highly pathogenic avian influenza virus pneumonia, hepatitis B, hepatitis C, and other infectious diseases. 2. Pregnant women or breastfeeding women. 3. Suspected metastatic lesions or confirmed pathological metastatic lesions. 4. Patients without examination records or incomplete information records, unable to be categorized into groups.

Design outcomes

Primary

MeasureTime frame
Serum circulating peptides;

Secondary

MeasureTime frame
sensitiveness;specificity;accuracy;

Countries

China

Contacts

Public ContactChunxue Bai

Zhongshan Hospital Affiliated to Fudan University

cxbai@fudan.edu.cn+86 186 2117 0011

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026