Recurrent Spontaneous Abortion
Conditions
Interventions
conventional treatment group:Intrauterine perfusion therapy
acupuncture group: Intrauterine perfusion therapy+acupuncture
Sponsors
Sichuan Jinxin Xi'nan Women's and Children's Hospital
Eligibility
Sex/Gender
Female
Age
21 Years to 40 Years
Inclusion criteria
Inclusion criteria: 1) Age: =40 years old; BMI<24; 2) Patients who meet the diagnosis of recurrent abortion and continue to have pregnancy planning; 3) Abnormal endometrial immune cell examination; 4) Have not received acupuncture treatment and have not participated in other clinical researchers in the past 3 months; 5) Sign the informed consent and volunteer to participate in this study. Note: Patients meeting the above criteria could be included in this study.
Exclusion criteria
Exclusion criteria: 1) There are obvious chromosomal abnormalities in previous embryos; 2) Chromosome abnormalities in couples; 3) uterine malformations or moderate to severe adhesions; 4) A clear diagnosis of infectious diseases; 5) Complicated with diabetes, hypertension, etc 6) Severe oligospermia of the male.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Rate of continuing pregnancy at 10 weeks;CD56 immune cell;CD68 immune cell;CD163 immune cell;CD1a immune cell;CD57 immune cell;CD8 immune cell;foxp3 immune cell;Detection of Th1/Th2 cytokines in peripheral blood;Proportion of NK cells in peripheral blood;Regulatory T cell; | — |
Secondary
| Measure | Time frame |
|---|---|
| Ultrasound of utrine receptivity;Ectopic pregnancy rate;Early abortion rate;Embryo implantation rate;Proportion of NK cells in peripheral blood;Regulatory T cell;CD138 immune cell;Live birth rate; | — |
Countries
China
Contacts
Public ContactYan Jia
Sichuan Jinxin Xi'nan Women's and Children's Hospital
Outcome results
None listed