Cesarean scar defect
Conditions
Interventions
Intervention group:Hysteroscopic niche resection
Sponsors
The International Peace Maternity and Child Health Hospital, School of Medicine, Shanghai Jiao Tong University
Eligibility
Sex/Gender
Female
Age
20 Years to 45 Years
Inclusion criteria
Inclusion criteria: (1)Age 20-45 years uterus cesarean scar defect and desire to be pregnant (2)Unexplained infertility for at least one year; or failed IVF; or problems during fertility therapy, such as intrauterine accumulation of fluid or difficulties in transferring embryo (3)Cesearen scar niche detected by MRI (a myometrial defect of at least 2mm depth at the site of scar and a residual myometrium of more than 2.2mm) (4)Signed informed consent.
Exclusion criteria
Exclusion criteria: (1)Contraindication to surgery or anaesthesia (general or local) (2)Established pregnancy (3)Relevant treatment affecting the observed indicators within 3 months (4)Combined cervical dysplasia, acute infection of the pelvis or acute attack of chronic infection, suspected or known malignancy or combined benign lesions requiring hysterectomy ( atypical endometrial cells), dysfunction of coagulation,hydrosalpinx communicating with the uterus (5)Infertility caused by ovulatory dysfunction, tubal disorders, endometriosis and submucosal fibroids (6)With myomas and oophoritic cyst that should be treated by operation (7)Contraindication to pregnancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pregnancy to live birth rate;cost-effect quota; | — |
Secondary
| Measure | Time frame |
|---|---|
| pregnancy outcome;menstruation characteristics;imaging measurements;perioperative complications; | — |
Countries
China
Contacts
Public ContactJinglan Liu
The International Peace Maternity and Child Health Hospital
Outcome results
None listed