central precocious puberty
Conditions
Interventions
Trail group:NA
Sponsors
Children's Hospital of Fudan University
Eligibility
Sex/Gender
All
Age
No minimum to 9 Years
Inclusion criteria
Inclusion criteria: 1.Children with clinical diagnosis of precocious puberty 2.Physical examination revealed a breast of Tanner Stage III or below 3.The syndrome differentiation of traditional Chinese medicine is Yin deficiency and fire flourishing syndrome 4.After reasonable prescription by the doctor, Dabuyin Pills was used for more than 3 months
Exclusion criteria
Exclusion criteria: 1.The clinical diagnosis was secondary precocious puberty 2.Continuous use of Dabuyin pills for less than 3 months 3.No major indicators (physical examination of sexual characteristics, B-ultrasound, sex hormones, etc.) were detected 3 months before and after treatment. 4.Zhibaidihuang Pills and/or Xuandiziyin mixture, Xiedingfang granules, Ziyinxihuo Fang and other traditional Chinese medicines used for the treatment of precocious puberty.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Tanner stage; | — |
Secondary
| Measure | Time frame |
|---|---|
| Uterine volume;Maximum follicle diameter;bone age;level of sex hormone(LH,FSH,PRL,E2,T,P);Ovarian volume; | — |
Countries
China
Contacts
Public ContactJian Yu
Children's Hospital of Fudan University
Outcome results
None listed