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Clinical study of remazolam tosylate combined with propofol for painless gastrointestinal endoscopy in the elderly

Clinical study of remazolam tosylate combined with propofol for painless gastrointestinal endoscopy in the elderly

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300074918
Enrollment
Unknown
Registered
2023-08-21
Start date
2023-08-21
Completion date
Unknown
Last updated
2023-08-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients scheduled for gastrointestinal endoscopy

Interventions

group A:Patients in group A were given the investigational drugs alfentanil, remazolam tosylate, and propofol according to the trial protocol.
group B:Patients in group B were given the investigational drugs alfentanil, and propofol according to the trial protocol.

Sponsors

People 's Hospital Of Ningjin
Lead Sponsor

Eligibility

Sex/Gender
All
Age
65 Years to 79 Years

Inclusion criteria

Inclusion criteria: (1) Patients scheduled for gastrointestinal endoscopy; (2) American Society of Anesthesiologists (ASA) physical status I to III; (3) Patients over 65 years of age (including 65 years of age); (4) Patients voluntarily participated in this study and signed informed consent.

Exclusion criteria

Exclusion criteria: (1) Patients who refused to participate in the trial; (2) Patients with a history of severe heart, brain, lung, liver, kidney and metabolic diseases; (3) Patients with a history of abnormal surgical anesthesia recovery; (4) Electrocardiogram showed heart rate 180 mmHg and/or diastolic blood pressure > 110 mmHg, or patients with hypotension < 90/60 mmHg; (7) Patients with neuromuscular system diseases and mental illness; (8) Patients with anemia; (9) Suspected abuse of narcotic analgesics or sedatives; (10) Patients who are predicted to have or have had difficult airways; (11) Patients who are uncooperative and unable to communicate.

Design outcomes

Primary

MeasureTime frame
Systolic blood pressure;Diastolic;Heart Rate;Respiratory rate;Oxygen saturation;Bispectral index;

Secondary

MeasureTime frame
Anesthesia induction time;Total inspection time;Emergence time;Patient Satisfaction Score;

Countries

China

Contacts

Public ContactLei Gaofeng

People 's Hospital Of Ningjin

njlgflgf@163.com+86 159 6976 5879

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026