Elderly patients scheduled for general anesthesia
Conditions
Interventions
Group A:Patients in group A were given the investigational drugs imazolam besylate, hydromorphone hydrochloride, and rocuronium bromide according to the trial protocol.
Group B:Patients in group B were given experimental drugs Sufentanil, propofol and rocuronium bromide according to the trial protocol.
Sponsors
People 's Hospital Of Ningjin
Eligibility
Sex/Gender
All
Age
65 Years to 79 Years
Inclusion criteria
Inclusion criteria: (1) Elderly patients scheduled for general anesthesia; (2) Patients aged 65-79 years, male or female; (3) Body mass index (BMI) 18.5 ~ 30 kg/m2; (4) American Society of Anesthesiologists (ASA) grade I ~ III; (5) Voluntary participation and signed informed consent.
Exclusion criteria
Exclusion criteria: (1) Patients who refused to participate in the trial; (2) Patients with a history of severe heart, brain, lung, liver, kidney and metabolic diseases; (3) Patients with a history of abnormal surgical anesthesia recovery; (4) Electrocardiogram showed heart rate 180 mmHg and/or diastolic blood pressure > 110 mmHg, or patients with hypotension < 90/60 mmHg; (7) Patients with neuromuscular system diseases and mental illness; (8) Patients with anemia; (9) Suspected abuse of narcotic analgesics or sedatives; (10) Patients who are predicted to have or have had difficult airways; (11) Patients known to be allergic to emulsion and opioids; (12) Patients who are uncooperative and unable to communicate.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Systolic blood pressure;Diastolic;Mean arterial pressure;Heart Rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Cardiac Output;Stroke Volume;Peripheral vascular resistance;Respiratory rate;Oxygen saturation;Bispectral index;Anesthesia induction time;Time from first dose to emergence;Time from last drug addition to emergence;Orientation recovery time; | — |
Countries
China
Contacts
Public ContactLiu Yuan
People 's Hospital Of Ningjin
Outcome results
None listed