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Study on the safety and efficacy of autologous fat-derived stromal vascular fraction( SVF ) in the treatment of knee joint injury

Study on the safety and efficacy of autologous fat-derived stromal vascular fraction ( SVF ) in the treatment of knee joint injury

Status
Recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300074894
Enrollment
Unknown
Registered
2023-08-18
Start date
2023-06-01
Completion date
Unknown
Last updated
2023-08-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

knee osteoarthritis

Interventions

SVF treatment group:SVF intra-articular injection, processing and production of cell implants, and then injected back to their patients.
routine treatment group:( 1 ) Muscle strength training : Let the patient sit on the treatment bed with both lower limbs suspended. First, the isotonic muscle strength training of the lower limb quadri
combined treatment group:SVF joint cavity injection + conventional treatment

Sponsors

Rehabilitation College of Gannan Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Aged 18-80 years old ; knee MRI, X-ray or arthroscopic diagnosis of unilateral KOA patients : Kellgren-lawrence rating III ( including ) below ; visual analogue scale ( VAS ) score was greater than 3 points. Willing to accept the treatment of this program, and voluntarily signed informed consent.

Exclusion criteria

Exclusion criteria: Active tumors, active inflammation, treponema pallidum, acquired immunodeficiency syndrome ( HIV ), hepatitis B virus, hepatitis C virus carriers ; patients with oral analgesia and other drugs ; hormonal therapy was used.

Design outcomes

Primary

MeasureTime frame
Western Ontario and McMaster Universities Osteoarthritis Index,WOMAC;

Secondary

MeasureTime frame
Range of motion;Visual analogue scale;

Countries

China

Contacts

Public ContactLiu Fei

The Third Affiliated Hospital of Gannan Medical University

815941561@qq.com+86 131 9813 2573

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026