Postoperative Neurocognitive Disorders
Conditions
Interventions
TEAS Group:Equipment: Huatuo SDZ-V. Intervention time: 30 minutes before the start of the surgery and 1 hour after the start of the surgery. Acupoint selection: Yintang, Shenting, Bilateral Neiguan, B
Control Group:Same as TEAS Group except for using internal broken wire.
Sponsors
National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Science and Peking Union Medical College
Eligibility
Sex/Gender
All
Age
65 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Aged > 65 years; 2. ASA I-III, activity tolerance > 4METs; 3. Planned to undergo elective laparoscopic surgery for gastrointestinal, esophagus, gynecological, hepatobiliary, pancreatic, and urinary system tumors, with an estimated surgery time of more than 3 hours; 4. Expected postoperative hospitalization time >= 5 days; 5. Can correctly understand related scale tests.
Exclusion criteria
Exclusion criteria: 1. Have a history of cognitive impairment, dementia, and delirium; 2. Concomitant presence of severe depression, schizophrenia, epilepsy, and Parkinson's disease; 3. Psychotropic drug abuse and opioid tolerance; 4. Severe visual and auditory impairment or inability to engage in normal speech communication; 5. Severe liver and kidney function or cardiac insufficiency; 6. Install an electric pacemaker; 7. There is trauma, nerve damage, or infection on the skin around the corresponding acupoints; 8. QT interval extension (male >= 460 ms, female >= 470 ms); 9. Recently received TEAS or acupuncture and moxibustion treatment or participated in other clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| In hospital postoperative neurocognitive disorders; | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative delirium;Postoperative cognitive disorders;NRS pain score;Length of stay after surgery;Length of ICU stay;Second surgery;Second Admission;30-day mortality;Quantitative assessment of brain functional status;Nausea and vomiting;Barthel index of ADL; | — |
Countries
China
Contacts
Public ContactHui Zheng
National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Science and Peking Union Medical College
Outcome results
None listed