Upper gastrointestinal endoscopy sedation
Conditions
Interventions
Group 1:Propofol is administered by intravenous injection at a dose of 0.5 µg/kg after 30 seconds of remifentanil administration and attempts to insert an endoscope are made approximately 60 seconds a
Group 2:Propofol is administered by intravenous injection at a dose of 0.3 µg/kg after 30 seconds of remifentanil administration and attempts to insert an endoscope are made approximately 60 seconds a
Sponsors
Women's and Children's Hospital affiliated to Qingdao University
Eligibility
Sex/Gender
All
Age
6 Years to 12 Years
Inclusion criteria
Inclusion criteria: 1. Age 6-12 years old. 2. American Society of Anesthesiologists (ASA) I or II. 3. Weight and Body Mass Index (BMI) within the normal range <30 kg/m2. 4. Guardian signs informed consent form.
Exclusion criteria
Exclusion criteria: 1. Known hypersensitivity to hydroquinone or patients with a history of severe allergies and family history of allergies. 2. Mental or neurological abnormalities. 3. Patients with severe dysfunction of the heart, liver, lungs, or kidneys. 4. Other conditions deemed unsuitable for participation in the trial by the researchers.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 50% Effective Dose of Ciprofol; | — |
Secondary
| Measure | Time frame |
|---|---|
| mean arterial pressure, MAP;heart rate, HR;SpO2;respiratory rate, RR;Onset time;recovery time; | — |
Countries
China
Contacts
Public ContactYueyi Ren
Women's and Children's Hospital affiliated to Qingdao University
Outcome results
None listed