Recurrent Implantation Failure
Conditions
Interventions
Routine treatment group:Intrauterine perfusion therapy
acupuncture group:Western medicine + acupuncture
Sponsors
Sichuan Jinxin Xi'nan Women's and Children's Hospital
Eligibility
Sex/Gender
Female
Age
21 Years to 40 Years
Inclusion criteria
Inclusion criteria: 1) Age: =40 years old;BMI<24; 2) Consistent with repeated planting failure; 3) Abnormal endometrial immune cell examination; 4) Have not received acupuncture treatment and have not participated in other clinical researchers in the past 3 months; 5) Sign the informed consent and volunteer to participate in the study. Note: Patients meeting the above criteria could be included in this study.
Exclusion criteria
Exclusion criteria: 1) Patients with drug allergy or allergic constitution; 2) Patients with severe endometrial adhesion; 3) Patients with endometrial tuberculosis 4) patients with serious primary diseases such as cardiovascular, liver, kidney and hematopoietic system and mental patients; 5) After examination, it is clear that the genital organs are malformed, genital tract inflammation or tumor; 6) Exposure to teratogenic radiation, poisons, drugs and in the period of action;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| clinical pregnancy rate;CD56 immune cell;CD68 immune cell;CD163 immune cell;CD1a immune cell;CD57 immune cell;CD8 immune cell;Foxp3 immune cell;CD138 immune cell;Detection of Th1/Th2 cytokines in peripheral blood;Proportion of NK cells in peripheral blood;Regulatory T cell; | — |
Secondary
| Measure | Time frame |
|---|---|
| Ultrasound of uterine receptivity;Ectopic pregnancy rate;Early abortion rate;Embryo implantation rate;Live birth rate;Biochemical pregnancy rate;Continuing pregnancy rate; | — |
Countries
China
Contacts
Public ContactYan Jia
Sichuan Jinxin Xi'nan Women's and Children's Hospital, Chengdu, Sichuan, PR China
Outcome results
None listed