Sepsis
Conditions
Interventions
Control group:The patient s healthy upper limb was adapted to remote ischemia of 60mmhg, inflated for 5 minutes, deflated for 5 minutes as a cycle, and a total of 4 cycles were completed. The interven
Intervention group:The patient s healthy upper limb was adapted to remote ischemia of 200mmhg, inflated for 5 minutes, deflated for 5 minutes as a cycle, and a total of 4 cycles were completed. The in
Sponsors
Tianjin medical university general hospital
Eligibility
Sex/Gender
All
Age
18 Years to 100 Years
Inclusion criteria
Inclusion criteria: 1. Age >= 18 years old, regardless of sex; 2. Meet the diagnostic criteria of sepsis (Sepsis 3.0); for patients with infection or suspected infection, sepsis can be diagnosed when the score of sequential (Sepsis-related) organ failure assessment (SOFA) rises by >= 2 points from the baseline; 3. Obtain informed consent and sign an informed consent form.
Exclusion criteria
Exclusion criteria: 1. Accompanied with severe cardiovascular disease, extremely critical condition, or cerebral hernia. Failure to fulfill the study is highly expected; 2. Accompanied with limb vascular occlusive disease, or with other diseases or conditions which cannot tolerate the intervention; 3. Other conditions that are not suitable for RIPC treatment, such as skin damage, severe thrombocytopenia, abnormal blood clotting, etc; 4. pregnant or lactating patients.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sequential Organ Failure Assessment Score(SOFA); | — |
Secondary
| Measure | Time frame |
|---|---|
| Baseline characteristics;Survival days without organ support;ICU stay time;hospital stay;in-hospital mortality;Laboratory indicators; | — |
Countries
China
Contacts
Public ContactLi Caifeng
Tianjin medical university general hospital
Outcome results
None listed