psoriasis
Conditions
Interventions
Sekukuniumab treatment group:NA
Routine treatment group for psoriasis (topical medication+acitretin):NA
Sponsors
First Affiliated Hospital of Kunming Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: (1) Age 18-70 years old, male or female. (2) Diagnosed with HIV infection combined with psoriasis (moderate to severe plaque psoriasis, pustular psoriasis, erythrodermic psoriasis, articular psoriasis), diagnosed by at least 2 deputy chief physicians, according to the "Chinese Psoriasis Diagnosis and Treatment Guidelines (2018 Edition)" and "China AIDS Diagnosis and Treatment Guidelines (2021 Edition)". (3) Those who receive and can adhere to antiviral therapy (ART). (4) HIV viral load was lower than the lower limit of detection (50 copies/ml), CD4+ T cell count > 200 cells/µl. (5) Be able to understand and voluntarily sign written informed consent. Be able to complete treatment and follow-up as required.
Exclusion criteria
Exclusion criteria: (1) Those who have used glucocorticoids or immunosuppressants in the past 4 weeks. (2) Those with other infectious diseases, such as active hepatitis, tuberculosis, etc. (3) Combined with other skin diseases, such as systemic lupus erythematosus, dermatomyositis, pemphigus, pemphigoid, etc. (4) Patients with tumors. (5) Psychiatric illness or disease of the nervous system (cognitive impairment) that affects the assessment. (6) Pregnant women or breastfeeding women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| PASI score;BSA score;DLQI score; | — |
Countries
China
Contacts
Public ContactLi yuye
First Affiliated Hospital of Kunming Medical University
Outcome results
None listed