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Clinical application of ultrasound-guided thoracic wall nerve block in off-pump coronary artery bypass grafting

Clinical application of ultrasound-guided thoracic wall nerve block in off-pump coronary artery bypass grafting

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300074809
Enrollment
Unknown
Registered
2023-08-16
Start date
2023-08-21
Completion date
Unknown
Last updated
2026-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Coronary Arteriosclerotic Heart Disease

Interventions

Experimental group :Performance of ultrasound-guided thoracic wall nerve block
Control group:Not performing ultrasound guided thoracic wall nerve block

Sponsors

The Second Affiliated Hospital, Army Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Aged 40-70 years old, with cardiac function of II to III (NYHA standard), scheduled for elective off-pump coronary artery bypass graft surgery under general anesthesia; 2. Signing of written informed consent.

Exclusion criteria

Exclusion criteria: 1. Allergies to local anesthetics or contraindications to ropivacaine; 2. Coagulopathy; 3. Infection at the injection site; 4. Previous neurologic or psychiatric disorders; 5. Uncontrolled diabetes, chronic obstructive pulmonary disease, abnormal liver function, and renal insufficiency (glomerular filtration rate < 15 mL/min/1.73m2). 6. Long-term opioid use, pregnancy, and inability to communicate with patients; 7. Use of other investigational drugs or participation in other clinical trials in the three months prior to selection for the study; 8. Patients who have previously undergone eye surgery or have abnormal pupils; 9. Patients who are unable to participate in the study for any reason or who are deemed unsuitable for participation in this study by the investigator.

Design outcomes

Primary

MeasureTime frame
(visual analogue scale, VAS) score in resting state; (visual analogue scale, VAS) score during coughing;

Secondary

MeasureTime frame
(visual analogue scale, VAS) score in resting state;(visual analogue scale, VAS) score during coughing;Total amount of sufentanil ;The first press time of patient controlled intravenous analgesia (PCIA);Number of patient controlled intravenous analgesia (PCIA) compressions in 48h;postoperative recovery time ;Time of tracheal tube removal;Ventilator support time;(intensive care unit, ICU) retention time;Removal time of chest wall drainage tube;Total hospitalization time;Surgery to discharge time;Hospital costs;Incidence of postoperative adverse actions;pupil diameter;

Countries

China

Contacts

Public ContactHong Li

Xinqiao Hospital of Army Medical University

lh78553@163.com+86 185 2381 0494

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026