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Clinical study for the safety and efficacy of high transcranial alternating current stimulation for treatment in schizophrenia

Clinical study for the safety and efficacy of high transcranial alternating current stimulation for treatment in schizophrenia

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300074775
Enrollment
Unknown
Registered
2023-08-16
Start date
2023-08-17
Completion date
Unknown
Last updated
2024-02-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Schizophrenia

Interventions

Sponsors

Beijing Huilongguan Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. 18-65 years old; 2. No gender limit; 3. Have a minimum education level of junior high school or above; 4. Patients diagnosed with SCZ according to the DSM-V criteria; 5. The total score of the PANSS scale is>=60; 6. The patient or family member agrees to participate in this study and signs an informed consent form.

Exclusion criteria

Exclusion criteria: 1. Intellectual disability; 2. Diagnosed as alcohol or other substance abuse or dependence (excluding nicotine or caffeine) (DSM-V criteria), with no sustained complete remission for at least 2 years prior to screening visits; 3. The patient is in pregnancy, breastfeeding, or planning to conceive; 4. Those who are severely excited, restless, restless, and unable to maintain a state of meditation; 5. Have a history of traumatic brain injury, stroke, brain tumor, Parkinson's disease, dementia, or epileptic seizures within the 6 months prior to enrollment; 6. Conduct electroconvulsive therapy (ECT) or non convulsive electroconvulsive therapy (MECT) within 6 months prior to enrollment; (Transcranial magnetic resonance needs to be discussed, and other physical therapies should also be considered); 7. Head skin inflammation, head trauma, etc; 8. Allergies to alcohol, adhesive tape, conductive paste, and metal electrodes; 9. Equipped with implantable electronic devices such as pacemakers, deep brain stimulators, etc; 10. Participants who are deemed unsuitable by the researchers to participate in this clinical trial.

Design outcomes

Primary

MeasureTime frame
Positive and Negative Syndrome,PANSS;MCCB;

Secondary

MeasureTime frame
The Scale for the Assessment of Negative Symptoms,SANS;fMRI;Clinical Global Impression;Auditory Hallucination Rating Scale (AHRS) Score;The Scale for the Assessment of Positive Symptoms,SAPS;paranoia;Multiple Object Tracking;

Countries

China

Contacts

Public ContactDeng Hu

Beijing HuiLongGuan Hospital

denghu501@163.com+86 83024081

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026