asthma
Conditions
Interventions
test team :Houpu Mahuang Decoction, Linggui Shugan Decoction, Mahuang Decoction Granule
control group :Houpu Mahuang Decoction, Linggui Zhugan Decoction and Mahuang Decoction were combined with placebo
Sponsors
The First Affiliated Hospital of Henan University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: (1) Patients who meet the diagnostic criteria for chronic duration of bronchial asthma; (2) Patients who meet the criteria of TCM syndrome diagnosis of bronchial asthma with external cold and internal drink syndrome; (3) Age =18 years and =80 years; (4) Did not participate in other clinical studies within one month before being selected; (5) Participate in the research voluntarily and sign the informed consent form.
Exclusion criteria
Exclusion criteria: (1) Pregnant and lactating women; (2) Patients with severe cardiovascular and cerebrovascular diseases (malignant arrhythmia, unstable angina pectoris, acute myocardial infarction, cardiac function grade 3 or above, stroke, cerebral hemorrhage, etc.); (3) Complicated with severe liver and kidney diseases (severe liver diseases refer to cirrhosis, portal hypertension and varicose bleeding, and severe kidney diseases include dialysis and kidney transplantation); (4) Patients with bronchiectasis, tuberculosis, pulmonary embolism or other severe respiratory diseases; (5) serious cognitive and mental disorders; (6) Those who are participating in other clinical trials within one month before being selected; (7) Patients who are allergic to known test drugs.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Asthma control test rate ;Number of acute attacks ; | — |
Secondary
| Measure | Time frame |
|---|---|
| Severity and hospitalization rate of acute asthma attack ;Dose of drug use ;pulmonary function ;fractional exhaled nitric oxide, feno ;Induced sputum inflammation phenotype ;eosinophil count ;Inflammation and immune factors ;Asthma control questionnaire ;Asthma quality of life score ; | — |
Countries
China
Contacts
Public ContactLi Suyun
The First Affiliated Hospital of Henan University of Traditional Chinese Medicine
Outcome results
None listed