ulcerative colitis
Conditions
Interventions
Sponsors
Qilu Hospital of Shandong University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: (1) ulcerative colitis group: ? through clear symptoms, colonoscopy and histopathology confirmed as ulcerative colitis; ?=18 years old and =70 years old; (2) Diarrheal IBS group: ? patients diagnosed with IBS according to the ROME-? criteria; ? Patients with diarrhea as the main manifestation; ?=18 years old and =70 years old; (3) Healthy control group: ? No intestinal diseases or only intestinal polyps; The patients participated in the study voluntarily and signed the informed consent.
Exclusion criteria
Exclusion criteria: (1) Current use of probiotics or antibiotics; (2) other inflammatory diseases of the colon; (3) Increased CRP or WBC in IBS group; (4) Patients in the IBS group had a history of bacterial overgrowth or infectious gastrointestinal disease in the past 6 months; (5) Complicated with serious heart, lung, liver and kidney diseases that may affect the results of this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Intestinal antimicrobial peptides; | — |
Secondary
| Measure | Time frame |
|---|---|
| Gut microbiota; | — |
Countries
China
Contacts
Public ContactYu Yanbo
Qilu Hospital of Shandong University
Outcome results
None listed