Microcirculatory dysfunction during PCI perioperative period
Conditions
Interventions
trial group:Standardized treatment+SYD
control group:Standardized treatment+SYD simulant capsules
Sponsors
Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing, China
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1) Age range from 18 to 85 years old; 2) Comply with NSTE-ACS diagnostic standards; 3) Agree to undergo coronary angiography; 4) Coronary angiography showed stenosis of the proximal and middle segments of the anterior descending branch exceeding 70% and agreed to receive PCI treatment; 5) Conforming to the diagnostic criteria for Qi deficiency and blood stasis syndrome of traditional Chinese medicine chest obstruction and heartache disease; 6) Voluntarily sign an informed consent form;
Exclusion criteria
Exclusion criteria: 1) Stable angina or acute ST segment elevation myocardial infarction; 2) Patients who require emergency PCI; 3) Patients who require coronary artery bypass grafting; 4) Individuals who are allergic to experimental drugs; 5) Severe cardiac insufficiency (left ventricular ejection fraction3 mg/dl or 265.2 umol/l); 8) Malignant tumors or hematological diseases; 9) Pregnant and lactating patients; 10) Regularly taking medication preparations containing traditional Chinese medicine ingredients in the first month before inclusion; 11) Require taking other traditional Chinese medicine preparations during clinical observation;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| index of microcirculatory resistance; | — |
Secondary
| Measure | Time frame |
|---|---|
| Cardiac function index;Serum myocardial necrosis markers;Inflammatory damage factor; | — |
Countries
China
Contacts
Public ContactHongxu Liu
Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing, China
Outcome results
None listed