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compare the diagnostic value of tNGS and mNGS for pathogeny in patients with immunocompromised pneumonia

compare the diagnostic value of tNGS and mNGS for pathogeny in patients with immunocompromised pneumonia

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300074695
Enrollment
Unknown
Registered
2023-08-14
Start date
2023-08-20
Completion date
Unknown
Last updated
2023-08-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

immunocompromised pneumonia

Interventions

Gold Standard:Medical history, clinical findings and laboratory results
Index test:mNGS and tNGS

Sponsors

Xuzhou Central Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: (1) Age =18 years old; (2) Immunosuppressed patients with a presumed diagnosis of pneumonia; (3) Willing to accept bronchoscopic alveolar lavage examination and physical condition permits; (4) The patient or guardian signs the informed consent.

Exclusion criteria

Exclusion criteria: (1) Patients may die 72 hours after enrollment; (2) Women during pregnancy or breastfeeding; (3) Patients receiving palliative care only.

Design outcomes

Primary

MeasureTime frame
The detection rate of infectious pathogens;—

Secondary

MeasureTime frame
sensitivity;specificity;drug resistance;—

Countries

China

Contacts

Public Contactli dan

Xuzhou Central Hospital

lidanlsy@163.com+86 181 1200 0229

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026