idiopathic normal pressure hydrocephalus
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: ?Patients without obvious headache symptoms, must have cognitive dysfunction, gait disorders and urinary incontinence one of the triad of gait disorders ; ?Head CT / MRI showed ventricular enlargement, frontal angle ratio ( Evans ' index ), that is, the maximum frontal angle width and the transverse diameter of the skull = 0.3 ; ?The cerebrospinal fluid pressure of lumbar puncture was less than 200 mmH2O, and the biochemical and routine examinations of cerebrospinal fluid were within the normal range. ?Adults over 18 years old, one month after the first diagnosis ; ?Can stand for 5 min without assistance ; ?MMSE > 17 points, can cooperate to complete the cognitive and gait assessment ; ?Sign the informed consent.
Exclusion criteria
Exclusion criteria: ?Unstable vital signs ; ?Serious heart, lung, kidney, liver and other organ diseases ; ?There was limb dysfunction before brain lesions ; ? Postural control abnormalities caused by other reasons, such as cerebellar diseases, vestibular system diseases, visual abnormalities, auditory abnormalities, peripheral nerve and musculoskeletal lesions ; ?Severe cognitive impairment, severe depression, aphasia, unable to cooperate with cognitive and balance assessment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| idiopathic normal-pressure hydrocephalus grading scale, iNPHGS; | — |
Secondary
| Measure | Time frame |
|---|---|
| Timed up and Go,TUG;Functional Reach Test,FRT;Multi-Directional Reach Test,MDRT;Berg Balance Scale,BBS;Modified Ashworth Scale,MAS;Montreal Cognitive Assessment,MoCA;ICF Activities and Participation Assessment Scale;Self-rating Anxiety Scale,SAS;Self-rating Depression Scale,SDS;Gait Analysis, GA; | — |
Countries
China
Contacts
Department of Rehabilitation Medicine, Huashan Hospital, Fudan University