Acute appendicitis
Conditions
Interventions
Experimental group:The preset value of 36+N is the baseline value of the new EEG closed-loop feedback guidance (the N value is 8-10 from the pre-experiment)
Control group:The original default value of 36 is the baseline value of EEG closed-loop feedback guidance (obtained from the team's previous research results)
Sponsors
Department of Anesthesiology, General Hospital of the Southern Theater of the People's Liberation Army Chinese People's Liberation Army
Eligibility
Sex/Gender
All
Age
18 Years to 55 Years
Inclusion criteria
Inclusion criteria: 1. Patients undergoing laparoscopic general anesthesia surgery with anesthesia duration > 60min, 2.18~55 years old, 3.BMI=18.5kg/m2, 4. ASA Class I~II
Exclusion criteria
Exclusion criteria: Exclude patients with any of the following criteria: 1. Contraindications to esketamine, propofol or refentanil; 2. Allergic reactions to egg/soy products; Hypersensitivity to fentanyl analogues; 3. Known/suspected neurological diseases, tumors, strokes, neurodegenerative diseases, severe head injuries, seizures, previous EEG abnormalities, cognitive deficits, acquired scalp/skull abnormalities, psychiatric diseases, severe depression, post-traumatic stress disorder, psychosis; 4. Taking psychotropic drugs within the past 7 days, 5. History of substance abuse/abuse or pregnancy in the past 30 days; 6. Currently involved in any other research involving drugs or devices.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| EEG value; | — |
Secondary
| Measure | Time frame |
|---|---|
| heart rate;Blood pressure;pulse; | — |
Countries
China
Contacts
Public ContactXu Bo
Department of Anesthesiology, General Hospital of the Southern Theater of the People's Liberation Army Chinese People's Liberation Army
Outcome results
None listed