Knee arthritis disease
Conditions
Interventions
Experimental Group:Local injection of liposome bupivacaine 266mg
Control group:Local injection of bupivacaine 150mg+ dexamethasone 5mg
Sponsors
Municipal Hospital of Heze
Eligibility
Sex/Gender
All
Age
50 Years to 80 Years
Inclusion criteria
Inclusion criteria: A total of 72 patients with knee osteoarthritis who received TKA under general anesthesia in our hospital from August 2023 to January 2024 were selected. ASA Level I or II. Selection criteria: (1) Age 50-80 years old; (2) The weight is 54 ~ 80kg.
Exclusion criteria
Exclusion criteria: Exclusion criteria: (1) poor compliance; (2) Allergy to the drugs in this study; (3) Daily intake of steroids or strong opioids (morphine, oxycodone, methadone, fentanyl, or ketomidone); (4) alcohol or drug abuse; (5) Rheumatoid arthritis.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Visual analogue scale (VAS) score and Ramsay sedation score were performed at 6h, 12h and 24h after surgery;The number of opiates the patient used post-operatively, and the actual number of PCIA compressions; | — |
Secondary
| Measure | Time frame |
|---|---|
| Patient's knee bend angle and first time of getting out of bed;The incidence of adverse reactions and postoperative satisfaction were compared between the two groups; | — |
Countries
China
Contacts
Public ContactLijun Qi
Municipal Hospital of Heze
Outcome results
None listed