Colorectal Neoplasms
Conditions
Interventions
Group A:Experimental group:Continuous intravenous injection of lidocaine
Group B: Control group:The same volume of normal saline will be administered during anesthesia and the postoperative PCA device
Sponsors
Nanfang Hospital of Southern Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Aged between 18 and 65 years; Elective laparoscopic colorectal resection; American Society of Anesthesiologists (ASA) physical status I-II; Written informed consent
Exclusion criteria
Exclusion criteria: Pregnant or lactating women; Inability to read, understand and communicate or psychiatric disorders; Failure to use a patient-controlled analgesia (PCA) device; History of abuse of opioids, steroids, and other analgesics; Severe primary diseases of the lung, liver, kidney, cardiovascular and hematopoietic systems or epilepsy; History of chronic upper limb pain or sensory disorders; Contraindication for propofol, opioids and lidocaine (eg, allergy, heart block, porphyrin disease); Actual body weight 80kg; Participated in other drug clinical trials within the past 3 months; Combined organ resection during the operation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| visual analog scale (VAS) score ; | — |
Secondary
| Measure | Time frame |
|---|---|
| First flatus and defecation;Total number of times that patients pressed the PCA button, including effective presses and ineffective presses;Quality of Recovery (QoR)40 score ;Total consumption of analgesic drugs (type and dosage) ;the incidence of postoperative nausea and vomiting;the length of hospital stay;the incidence of postoperative complications;I-FEED score;VAS pain scores within 3 days postoperatively; | — |
Countries
China
Contacts
Public ContactLin Chunshui
Nanfang Hospital of Southern Medical University
Outcome results
None listed