Patients who plan to undergo Elective surgery under general anesthesia and mechanical ventilation
Conditions
Interventions
Case series:None
Sponsors
West China Hospital of Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1) The Elective surgery patients under general anesthesia and mechanical ventilation in West China Hospital of Sichuan University from June 2023 to June 2024 were selected; 2) Intraoperative intravenous anesthesia maintenance drugs include propofol; 3) 18 years = age<65 years; 4) 18.5 kg/m2 = Body Mass Index (BMI) = 30 kg/m2; 5) The American Society of Anesthesiologists (ASA) is classified as I-III;
Exclusion criteria
Exclusion criteria: (2) Exclusion criteria: 1) Patients with metabolic disorder and Endocrine disease such as diabetes and thyroid dysfunction before operation; 2) Preoperative patients with history of cardiovascular disease, cardiac dysfunction, arrhythmia and hypertension; 3) Patients with severe liver and kidney dysfunction before surgery; 4) Patients with acute or chronic lung disease or a history of lung surgery prior to surgery; 5) Patients with preoperative anemia (male: Hb<120g/L; female: Hb<110g/L); 6) Preoperative patients with Central nervous system disease and long-term use of psychotropic drugs; 7) Individuals with a history of excessive drinking and smoking; 8) Those who are allergic to soybeans and Milk allergy, and those who may be allergic to propofol; 9) Patients who have participated in other clinical trials in the past three months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| concentration of exhaled propofol ; | — |
Secondary
| Measure | Time frame |
|---|---|
| SBP,DBP,MAP;Bispectral index;heart rate; | — |
Countries
China
Contacts
Public ContactZhang Wensheng
West China Hospital of Sichuan University
Outcome results
None listed