rosacea
Conditions
Interventions
Minocycline combined with radiofrequency induction of compound lidocaine cream:Radiofrequency induction of compound lidocaine cream
Minocycline combined with radiofrequency induction of physiological saline:Radiofrequency induction of physiological saline
Sponsors
West China Hospital, Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Patients with rosacea diagnosed according to the Guidelines for the diagnosis and treatment of rosacea in China (2021 edition) and accompanied by obvious facial conscious symptoms, including itching, burning, tingling and swelling. 2. Age range: 18-60 years old. 3. Participants who are informed of and have signed the informed consent form for this study.
Exclusion criteria
Exclusion criteria: 1. Having other skin diseases on the face, such as acne, melasma, freckles, and seborrheic dermatitis, may affect the judgment of the test results. 2. Individuals who are allergic to the investigational drug and matrix or have a hypersensitive constitution. 3. Pregnant or breastfeeding women or those planning to become pregnant. 4. Patients who have received drug treatments within the last month, such as pregabalin, NSAIDS and antihistamines. 5. Patients who have used calcineurin inhibitors on the face within 3 months. 6. Patients who have received any other chemical, physical, or medication treatment on the face within the last month. 7. Patients who have received facial injection or surgical treatment within 2 months. 8. Patients with immunodeficiency diseases.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Conscious symptom relief rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| IGA score;Dermatology life quality index;Rosacea life quality index;Dermoscopy;Red zone score of VISIA;Transepidermal Water Loss;Stratum Corneum Hydration; | — |
Countries
China
Contacts
Public ContactXiang Wen
Department of Dermatology, West China Hospital, Sichuan University.
Outcome results
None listed