type 2 diabetes mellitus with overweight or obesity
Conditions
Interventions
aerobic exercise:Three sessions of aerobic exercise will be performed in the afternoon and evening of the first day and in the morning of the second day. The duration of each exercise session will be
resistance exercise:A total of 3 resistance exercises will be performed in the afternoon and evening of the first day and the morning of the second day. A 5-min warm-up on a power bike (exercise inten
Sponsors
National Fitness and Scientific Exercise Research Center, China Institute of Sport Science
Eligibility
Sex/Gender
All
Age
55 Years to 70 Years
Inclusion criteria
Inclusion criteria: ? Meeting WHO diagnostic criteria for type 2 diabetes; ? 25kg/m2 = BMI <35kg/m2 (WHO); ? HbA1c between 6.5 and 11% in the last 3 months; ? Basic glucose-lowering treatment regimen without injectable insulin promoters, insulin; ? 55-70 years old, 50/50 male and female (6 males and 6 females); ? No physician-emphasized contraindications to exercise (e.g., severe heart disease, arthritis, limb disorders, osteoporosis, history of fracture, etc.), with the ability to care for themselves and basic exercise capacity; ? No metal grafts, etc. in the body; ? Agree to participate in three energy metabolism chamber test experiments.
Exclusion criteria
Exclusion criteria: ? Uncontrolled hypertension (resting blood pressure = 160/100 mmHg); severe cardiovascular and cerebrovascular disease, respiratory disease, hepatic and renal insufficiency, malignancy and other chronic wasting diseases, active infection and a history of surgery involving vital organs in the past 3 months; ? Acute complications of diabetes (diabetic ketoacidosis, hyperosmolar state, infection) occurred in the past 3 months, or the presence of one or more serious chronic complications of diabetes, such as severe cardiovascular and cerebrovascular pathology (angina pectoris, myocardial infarction, grade III-IV heart failure, severe arrhythmias, transient ischemic attack, stroke, etc.), massive proteinuria (urinary albumin/creatinine ratio = 300 mg/g ), severe diabetic foot, severe neuropathy, blurred vision; ? Those who did not pass the pre-experimental mental status assessment (PHQ-9 , SAS, verbal questioning about the presence of claustrophobia). Those with depression, anxiety or claustrophobia, etc.; those with severe sleep disorders. Those taking psychotropic drugs or insomnia drugs; ? Those who participated in other clinical trial programs in the past 3 months or currently, those who participated in regular physical activity in the past 6 months (150 min of moderate-to-vigorous physical activity per week); ? Those whose weight loss within 3 months exceeded 5% of initial weight; ? Those who smoked daily and could not stop smoking (occasional smokers could be included), and those who drank alcohol daily and could not stop drinking (occasional drinkers could be included); ? Those who failed the pre-exercise risk screening and assessment (PAR-Q); Those who diagnosed by doctors as osteoporosis or fracture who are not suitable to participate in the exercise intervention program in this study; ? Those with language expression impairment as judged by the researcher through communication and unable to communicate with the testers outside the chamber with immediate signals.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| energy expenditure; | — |
Secondary
| Measure | Time frame |
|---|---|
| Dynamic glucose monitoring;heart rate;physical activity;blood pressure; | — |
Countries
China
Contacts
Public ContactJingjing Wang
National Fitness and Scientific Exercise Research Center, China Institute of Sport Science
Outcome results
None listed