immunity
Conditions
Interventions
Control group:Common infant formula
Experimental group:Bovine lactoferrin supplementation of infant formula
Sponsors
Affiliated Hospital of Jiangnan University
Eligibility
Sex/Gender
All
Age
12 Months to 13 Months
Inclusion criteria
Inclusion criteria: Age 12 to 13 months ; physical health, and height and weight according to ' China growth and development of children under 7 reference standard ' are in the normal range.
Exclusion criteria
Exclusion criteria: Patients with severe milk protein allergy or family history ; patients with lactose intolerance or family history ; those whose height and weight development did not reach the standard ; severe, persistent or chronic diarrhea ; severe infection requiring hospitalization in the previous month ; severe chronic diseases ; with underlying diseases ( including but not limited to : pediatric kidney disease, hyperactivity and other mental illness, leukemia, etc. ).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| intestinal flora;blood routine;immunoglobulin;calprotectin;secretory IgA;SCFAs; | — |
Secondary
| Measure | Time frame |
|---|---|
| Head circumference;Weight;Height; | — |
Countries
China
Contacts
Public ContactHong Cao
Affiliated Hospital of Jiangnan University
Outcome results
None listed