Patients undergoing breast surgery under general anesthesia
Conditions
Interventions
Control group:No drug use before surgery
Experimental group:Acetaminophen mannitol injection 500mg, intravenous injection 15min
Sponsors
The First Affiliated Hospital of Henan University of Chinese Medicine
Eligibility
Sex/Gender
Female
Age
18 Years to 50 Years
Inclusion criteria
Inclusion criteria: (1) Those who plan to undergo elective breast surgery under general anesthesia; (2) Age 18-50 years old, BMI 15-40 kg/m2, ASA I-III grade; (3) Able to understand and sign informed consent forms, and cooperate in completing interventions and evaluations.
Exclusion criteria
Exclusion criteria: (1) Pregnant and lactating patients; (2) Determine/suspect a history of alcohol, opioid, or other substance abuse; (3) Postoperative ICU admission; (4) Participate in other clinical studies within 3 months prior to enrollment in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| VAS; | — |
Secondary
| Measure | Time frame |
|---|---|
| Number of cases of nausea and vomiting;Intraoperative remifentanil dosage;Number of cases of analgesic remedy within 48 hours after surgery;Postoperative hospitalization days and total hospitalization days;PONV related complications 30 days after surgery; | — |
Countries
China
Contacts
Public ContactZhifeng Lyu
The First Affiliated Hospital of Henan University of Chinese Medicine
Outcome results
None listed