coronary artery disease
Conditions
Interventions
POAF:Observational study,inapplicable
non-POAF:Observational study,inapplicable
Sponsors
General Hospital of Northern Theater Command
Eligibility
Sex/Gender
All
Age
35 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1) 35-80 years old, regardless of gender; 2) Sinus rhythm before operation, no history of atrial fibrillation and atrial arrhythmia; 3) Selective off-pump coronary artery bypass grafting (bypass grafts were internal mammary artery and/or great saphenous vein); 4)EF>40%; 5) Good compliance, able to cooperate with the completion of follow-up.
Exclusion criteria
Exclusion criteria: 1)Those who do not meet the selection criteria; 2)Emergency or second cardiac surgery; 3)History of arrhythmia, congenital heart disease, valvular heart disease, tumor disease, hyperthyroidism or hypothyroidism recorded by medical documents; 4)Use of antibiotics within two weeks; use of probiotics or yogurt within one week; chronic or acute gastrointestinal disease within one month; 5)Those who need to take class I and class III antiarrhythmic drugs; 6)History of atrial fibrillation ablation and pacemaker implantation; 7)Severe liver and kidney dysfunction (test results exceed 3 times the upper limit of normal value), severe lung disease, coagulation dysfunction; 8)Patients with other diseases requiring radiotherapy, chemotherapy and long-term hormone therapy; 9) Those who have participated in other clinical trials or refused to participate in this trial;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| preoperative Gut Microbiota ;preoperative plasma metabolites ;postoperative plasma metabolites ; | — |
Countries
China
Contacts
Public ContactWang Huishan
General Hospital of Northern Theater Command
Outcome results
None listed