Fibrosing mediastinitis
Conditions
Interventions
case series:Nil
Sponsors
Gansu Provincial Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1)Pulmonary hypertension was diagnosed by right heart catheterization (RHC), defined as mean pulmonary artery pressure (mPAP) > 20mmHg; 2) Chest computed tomography (CT) manifests as focal or diffuse hyperplasia of fibrous tissues compressing adjacent structures (vascular, airway, or esophageal) with or without calcification.
Exclusion criteria
Exclusion criteria: 1) Patients with mediastinal malignancies and/or prior mediastinal radiation therapy; 2) Patients with mediastinal necrotizing granulomatous lymphadenitis, systemic sclerosis, and other diseases that cause hyperplasia of tissues within the mediastinum; 3) mean pulmonary artery pressure (mPAP) = 20 mmHg by RHC; 4) concomitant with other types of pulmonary hypertension; 5) comprised serious concomitant diseases, or significant impairment of organ function;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| survival ; pulmonary vascular resistance; | — |
Secondary
| Measure | Time frame |
|---|---|
| mean pulmonary artery pressure;systolic pulmonary artery pressure;diastolic pulmonary artery pressure; cardiac index;mixed venous oxygen saturation;tricuspid annual plane systolic excursion;N-terminal pro-brain natriuretic peptide;World Health Organization Functional Class;6-minute walking distance;right atrial area; | — |
Countries
China
Contacts
Public ContactYunshan Cao
Gansu Provincial Hospital
Outcome results
None listed