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The optimized prescription mining of Jianpi Tongluo Jiedu method in the treatment of chronic atrophic gastritis and its effect on inflammation of gastric mucosal

The optimized prescription mining of Jianpi Tongluo Jiedu method in the treatment of chronic atrophic gastritis and its effect on inflammation of gastric mucosal

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300074536
Enrollment
Unknown
Registered
2023-08-09
Start date
2023-08-10
Completion date
Unknown
Last updated
2023-08-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

chronic atrophic gastritis

Interventions

Sponsors

Guang'anmen Hospital, China academy of Chinese medical sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 75 Years

Inclusion criteria

Inclusion criteria: (1) those who meet the CAG diagnosis, with or without IM and mild Dys; ? All patients should be CAG patients from Yao Naili's team expert's clinic; (3) There are two gastroscopy and histopathological results within 3 years, and the data are complete; ? Histopathological results suggest that the degree (grade) of chronic inflammation and active inflammation in patients is reduced or unchanged; (5) Between the two gastroscopy examinations, the method of Jianpi Tongluo Jiedu (related drugs) was used, and the treatment duration exceeded 60% of the total course of treatment; (6) The age is between 20 and 75 years old.

Exclusion criteria

Exclusion criteria: (1) those who have been proved to be cancerous by pathological examination, or those who belong to severe Dys (intraepithelial neoplasia); Or Dys appears newly after treatment, or changes from mild Dys to severe Dys; ? Hp infection and anti-Hp treatment during two gastroscopy were successful; ? Long-term use of drugs that affect gastric mucosa, such as Morodan, Weifuchun, Teprenone, etc., is more than half of the course of taking traditional Chinese medicine for Jianpi Tongluo Jiedu; (4) Those who are known to be allergic to any drug component of this prescription or are allergic constitution; (5) Patients with severe heart, liver and renal insufficiency, severe hypertension, diabetes and coronary heart disease can't be controlled by drugs; (6) Pregnant or lactating women; (7) Suspected or indeed having a history of mental illness, and a history of alcohol and drug abuse.

Design outcomes

Primary

MeasureTime frame
Pathological changes of gastric mucosa;

Countries

China

Contacts

Public ContactBAI Yuning

Guang'anmen Hospital, China academy of Chinese medical sciences

byn-1973@163.com+86 133 6626 6838

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026