Pain after tonsillectomy in children
Conditions
Interventions
Experimental group:Ibuprofen suspension
Control group:Paracetamol oral suspension
Sponsors
Anesthesia Surgery Center, West China Hospital, Sichuan University
Eligibility
Sex/Gender
All
Age
3 Years to 14 Years
Inclusion criteria
Inclusion criteria: 1) Age 3-14 years old, gender unlimited; 2) Tonsillectomy or tonsillectomy combined with adenoidectomy under elective general anesthesia, including traditional tonsillectomy and low-temperature plasma resection; 3)ASA classification: I-II; 4)Volunteer to participate in this study and sign a written informed consent.
Exclusion criteria
Exclusion criteria: 1) Patients who are allergic to NSaids and other investigation-related drugs; 2) Patients with a history of asthma; 3) Children with a history of gastrointestinal bleeding; 4) Abnormal coagulation function or platelet function (such as hemophilia); 5) The drug in process has been taken within 30 days prior to administration. 6) Patients with liver and kidney insufficiency
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Area under the time curve (AUC) of pain score during swallowing 24 hours after surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of waking agitation;Area under time curve (AUC) of resting pain score 24h after surgery;Incidence of postoperative nausea and vomiting;The incidence of postoperative bleeding;Time of first postoperative feeding;Postoperative wound recovery;Patient satisfaction; | — |
Countries
China
Contacts
Public ContactFei Liu
Anesthesia Surgery Center, West China Hospital, Sichuan University
Outcome results
None listed