Skip to content

Application and mechanism of GDFT combined with different anesthesia methods and drugs in the perioperative period of thoracic surgery in elderly patients

Application and mechanism of GDFT combined with different anesthesia methods and drugs in the perioperative period of thoracic surgery in elderly patients

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300074475
Enrollment
Unknown
Registered
2023-08-08
Start date
2023-09-01
Completion date
Unknown
Last updated
2023-08-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lung tumors in elderly patients

Interventions

Goal-directed fluid therapy group:svv <13% by infusion of colloid and vasoactive drugs
Restricted rehydration group:Restricted rehydration

Sponsors

Affiliated Hospital of Chengde Medical College
Lead Sponsor

Eligibility

Sex/Gender
All
Age
65 Years to 85 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Elderly patients (60-75 years old) who were to undergo elective thoracoscopic lobectomy. Expected OLV (one-lung ventilation) time of 1h-2h. BMI: 18.5-23.9 kg/m2.

Exclusion criteria

Exclusion criteria: Exclusion criteria: Refusing to participate. Hearing and/or visual impairment resulting in an inability to complete gastrointestinal function assessment. Preoperative comorbid digestive disorders affecting gastrointestinal motility. American Society of Anesthesiologists (ASA) classification > III. Comorbid severe hypertension, heart disease, and other significant organ dysfunction. History of alcoholism or drug dependence.

Design outcomes

Primary

MeasureTime frame
motilin;gastrin;intestinal fatty acid binding protein;

Secondary

MeasureTime frame
First exhaust time;Time of first defecation;First time out of bed;Total hospitalization time;Mean arterial pressure;Heart rate;Urine volume;Colloid infusion volume;Total number of infusions;Incidence of nausea and vomiting;

Countries

China

Contacts

Public ContactDuan Fengmei

Affiliated Hospital of Chengde Medical College

623408892@qq.com+86 150 2896 0124

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 8, 2026