proximal gastric cancer
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Voluntarily participate in the study and sign informed consent; (2) Preoperative CT or endoscopic ultrasound confirmed that the lesion was T1 or T2 proximal gastric cancer without lymph node metastasis. All patients did not receive preoperative radiotherapy or chemotherapy, which may affect the outcome. Both male and female, aged =18 years old and = 75 years old; 3. Expected survival time =3 months; 4.ECOG score 0-1; 5. At least one measurable tumor lesion: long diameter =10 mm, short diameter of lymph node =15 mm on spiral CT; The maximum diameter should be =20mm by CT or physical examination. 6. No major organ failure; 7. No severe coagulation dysfunction; 8. Patients who can tolerate electronic gastroscopy.
Exclusion criteria
Exclusion criteria: 1. Intestinal obstruction;2. Extensive adhesion in the peritoneal cavity;3. Obvious inflammation in the abdominal cavity;4. There are high risk factors for poor anastomotic healing, including anastomotic edema, ischemia, obvious tension, severe hypoproteinemia, etc.5. Major organ dysfunction such as heart, kidney, liver and brain;6. Cachexia;7. Severe bleeding and coagulation disorders;8. Patients with severe or uncontrolled cardiovascular and pulmonary diseases, or unstable vital signs due to various reasons;9. Pregnant and lactating women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| overall survival;progression free survival;Operation time;Lymph node dissection;R0 resection or not;Gastrointestinal function recovery time;Gastroscope;Tumor markers;Nutrition indicators;Blood routine ;Histopathology;Imaging examination;TNM staging;clinical manifestations;immunological markers; | — |
Secondary
| Measure | Time frame |
|---|---|
| anastomosis time;Intraoperative blood loss;Postoperative hospital stay;Time of drainage tube removal;Infectious indicators;Liver function;Coagulation function; | — |
Countries
China
Contacts
Second Hospital of Lanzhou University