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Application of fNIRS-based brain functional connectomics in PD gait disorder

Application of fNIRS-based brain functional connectomics in PD gait disorder

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300074453
Enrollment
Unknown
Registered
2023-08-07
Start date
2023-08-10
Completion date
Unknown
Last updated
2023-08-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Parkinson disease

Interventions

rehabilitation group:exercise
control group:none

Sponsors

Tianjin Huanhu Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: (1) Voluntarily participate in this research and sign the informed; (2) Age 18-75 years old, age = 18 years old at the time of signing the informed consent form, gender is not limited; (3) Clinically confirmed Parkinson's disease diagnosed according to the diagnostic criteria for Parkinson's disease in China (2016 edition) and MDS diagnostic criteria. (4) Parkinson's disease specialist determined the existence of gait disorder according to clinical manifestations, and the gait analyzer evaluated the abnormalities in time parameters and spatial parameters and MDS-UPDRS III-11>1 points, and the medication regimen did not fluctuate frequently. (5) Normal cognitive function, MMSE > 24 points. (6) No contraindications to near-infrared test, severe liver and kidney dysfunction, cardiac insufficiency, etc (7) Imaging evaluation of abnormalities and evidence of damage to the structure of the brain parenchyma (such as infarction foci, etc.)

Exclusion criteria

Exclusion criteria: (1) There is obvious cognitive impairment and cannot complete training. (2) Those with other cardiopulmonary diseases who are not suitable for rehabilitation training. (3) Those who have osteoarticular diseases and cannot complete training. (4) Those who are older than 75 years old or less than 18 years old. (5) History of Parkinson's disease surgery (including: DBS and destruction, etc.).

Design outcomes

Primary

MeasureTime frame
motor function;

Secondary

MeasureTime frame
gait analysis;

Countries

China

Contacts

Public Contactzhu zhizhong

tianjin huanhu hospital

zhu36121209@sina.com+86 22 5906 5605

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Jun 20, 2026