Endometriosis
Conditions
Interventions
Transvaginal surgery group:no
Transabdominal or laparoscopic surgery group :no
Sponsors
Peking Union Medical College Hospital, Chinese Academy of Medicine Sciences
Eligibility
Sex/Gender
Female
Age
20 Years to 45 Years
Inclusion criteria
Inclusion criteria: (1) Informed consent has been signed (2) Women of reproductive age: 20-45 years old (3) Obvious clinical symptoms: such as dysmenorrhea, pain during intercourse, pain in bowel movements, and anal distention, etc., tuberous mass in rectovaginal septum (=1cm) or visible blue-purple nodules can be found in the posterior fornix of vagina. (4) Imaging examination (ultrasound or MRI) revealed nodular mass in the rectovaginal septum, which is consistent with the symptoms of endometriosis (5) The pathological diagnosis after surgery is rectovaginal endometriosis (6) Clear indications for surgery
Exclusion criteria
Exclusion criteria: (1) Patients who participate in other interventional research projects outside of routine clinical treatment (2) Patients with poor living condition, incapacitation or loss of consciousness. (3) Patients who refused to participate in the study. (4) Patients with concomitant or diagnosed malignant tumor. (5) Patients with obstructive intestinal abnormalities were identified (6) Patients with other intestinal diseases or previous history of intestinal surgery (7) Co-existing diseases or taking related drugs that may affect intestinal function (8) There is contraindication of hormone drugs
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Health-related quality of life; | — |
Secondary
| Measure | Time frame |
|---|---|
| the relief of pain associated with endometriosis;The number and proportion of patients with symptoms such as constipation, anal dropsy and distension, and posterior tenesmus;the time of recurrence and the proportion of reoperation;change of the rectovaginal endometriosis lesion;Gastrointestinal quality of life index;the number and percentage of adverse events and serious adverse events after surgery;he change of CA125,CA199,AMH, six sex hormones before and after operation;Proportion of patients who require medication before and after surgery;The direct economic costs of different treatments;The patient's overall impression of the treatment effect; | — |
Countries
China
Contacts
Public ContactYi Dai
Peking Union Medical College Hospital, Chinese Academy of Medicine Sciences
Outcome results
None listed