dry eye
Conditions
Interventions
Group A1:SMILE?Routine medication
Group B1:SMILE?Diquafosso sodium eye drops
Group A2:Routine medication
Group B2:Diquafosso sodium eye drops
Sponsors
Ethics Committee of the Eye Hospital of Shandong University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 35 Years
Inclusion criteria
Inclusion criteria: 1. Age 18-35 years old; 2. The research eye meets the conditions of FS-LASIK or SMILE surgery (in line with the "Expert Consensus on Clinical Diagnosis and Treatment of Laser Corneal Refractive Surgery (2015)" or "Expert Consensus on the Surgical Specifications of Corneal Stromal Lens Removal with Femtosecond Laser Small Incision in China (2018)"); 3. Preoperative diagnosis of normal or mild dry eye by refractive surgery (in line with the "Chinese Expert Consensus on Dry Eye: Examination and Diagnosis (2020)"); 4. Diopter =-6D, cylindrical lensity =5D (high myopia is more likely to occur dry eye, "Chinese corneal refractive surgery perioperative dry eye diagnosis and treatment experts")
Exclusion criteria
Exclusion criteria: 1. Those who have a history of allergy to the test drug or its ingredients or cannot tolerate adverse reactions; 2. Previous eye disease, surgical history, ocular trauma and systemic disease; 3. Patients who have participated in other clinical trials within 1 month before surgery, and have used drugs that affect ocular surface function within 6 months before surgery; 4. Pregnant and lactating women, or women planning to become pregnant during the course of the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Uncorrected visual acuity (UCVA);Dioptric;Tear break up time (TBUT); | — |
Secondary
| Measure | Time frame |
|---|---|
| Tear meniscus height;Fluorescent (FL);Ocular Surface Disease Index, (OSDI);Corneal central thickness;Corneal nerve density; | — |
Countries
China
Contacts
Public ContactJi Peng
Affiliated Eye Hospital of Shandong University of Traditional Chinese Medicine
Outcome results
None listed