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Effects of esketamine venous self-controlled analgesia on chronic postoperative pain and long-term quality of life in thoracoscopic surgery patients:One randomized controlled, double-blind study

Effects of esketamine venous self-controlled analgesia on chronic postoperative pain and long-term quality of life in thoracoscopic surgery patients:One randomized controlled, double-blind study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300074355
Enrollment
Unknown
Registered
2023-08-04
Start date
2023-09-01
Completion date
Unknown
Last updated
2023-08-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic postoperative pain in patients undergoing thoracoscopic surgery

Interventions

Esketamine Group (AGroup):The prescription of intravenous self-control analgesia pump contains Esketamine (The remaining drugs are the same as the control group)
control group(BGroup):The prescription of intravenous self-control analgesia pump does not contain Esketamine

Sponsors

Pidu District People’s Hospital, Chengdu
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Patients who meet the criteria for elective thoracic lobectomy from October 2022 to December 2023 in Pidu District People's Hospital. (1) 18 years old= age = 60 years old; (2) ASAI ~ II grade; (3) Patients who intend to electively undergo thoracoscopic lobectomy.

Exclusion criteria

Exclusion criteria: Exclusion criteria: (1) Combined with serious physical diseases, such as uncontrolled hypertension, coronary heart disease, intracranial vascular malformation, asthma attack, severe liver and kidney dysfunction, etc.; (2) Those with a history of epilepsy; (3) Those with a history of manic episodes; (4) Those who are allergic to the test drug: (5) pregnant and lactating women: (6) Patients with glaucoma; (7) Bipolar disorder, or other mental illnesses or mental retardation; (8) Patients under short-term or long-term influence of alcohol: (9) Patients who have difficulty communicating and patients who are unwilling to cooperate.

Design outcomes

Primary

MeasureTime frame
The incidence of postoperative neuropathic pain;

Secondary

MeasureTime frame
Pain score during postoperative 24-hour activity;Pain score at rest 24 hours after surgery;EQ5D scale scores and chronic postoperative pain levels at 1 month, 6 months, and 12 months after surgery;Postoperative adverse reactions;

Countries

China

Contacts

Public ContactLi Junxiang

Pidu District People’s Hospital, Chengdu

dr2002@163.com+86 183 4930 1952

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026